A globally standardized approach in high and low and middle-income countries (LMIC) to actively monitor the safety of vaccines for pregnant women during development and implementation phases is critical. Brighton Collaboration’s (BC) Global Alignment of Immunization Safety Assessment in Pregnancy (GAIA) project has developed globally standardized case definitions (CDs) of key obstetric and neonatal terms for the assessment of safety of vaccines in pregnancy. CDs are categorized into levels of diagnostic certainty, facilitating their use in varied settings. This study evaluates the field performance of CDs in LMIC.

We are proud to have quite a few IMPRINT members amongst the authors of a recent publication on neonatal immune ontogeny published in Nature Communications. It describes a novel way of getting maximum information from minimum samples and not only the data but also the methodology might be of relevance to some of our IMPRINT network members:

Dynamic molecular changes during the first week of human life follow a robust developmental trajectory. https://doi.org/10.1038/s41467-019-08794-x

Our challenge 4 co-lead and director of the Vaccine Confidence Project, Heidi Larson commented on urban anti-vaccine hotspots putting children at risk, and the still ongoing misconception about the relationship between the MMR vaccine and autism.